When you are done with your site, check out how it looks from a visitors standpoint. Did you get across everything that you wanted? Go to your site from someone else's computer to get their point of view and write down the changes that you will need to make to continually improve the aesthetics.
Use your footers wisely. People often scroll to the bottom of a page to find out who runs the site, how to contact the owner or to see how fresh the content is based on a copyright date. You can even include a short biography or other information you feel is pertinent.
Remove any content or comments that don't add value to your blog. That way, the site stays suitable for the interested folks who read it. Akismet is one of the better plugins for filtering out spam.
If you are new to WordPress, make sure to keep your sidebar simple. Make sure that it only has the essentials. Your visitors shouldn't have to weed through a ton of ads and banners to find the links they want to click on. Try removing the items in Appearance & Widgets that don't contribute anything to your cause or business.
It is important that if you're serious about blogging, then you really research all there is to know about WordPress. Anything about blogging can become confusing or appear to be hard, but knowledge is your key to success. Just by reading this article, you have taken the first step to becoming a great blogger.